World War II combat nurse Claire Randall is transported back to 1743 Scotland, where she is kidnapped by Highlanders and meets an injured man named Jamie.
Claire is taken to meet the Laird and befriends the mysterious Geillis Duncan; the clan decides to keep Claire as a prisoner after they learn of her medical skills.
Jamie helps Claire tend to a sickly child; a story told during an evening's entertainment gives Claire hope for her freedom.
Claire plans to attempt an escape during the "Gathering," but her plans are thwarted by a run-in with a drunken Dougal and a surprise encounter with Jamie.
Claire is brought along on the MacKenzie rent-collecting trip; Dougal uses Jamie's scars to drum up sympathy for the Jacobite cause; Claire remembers that a famous moment in Scottish history will soon occur.
Claire has an unexpected meeting with a British general; Capt. Jack Randall is determined to uncover Claire's secrets.
Claire and Jamie's unfolding marriage causes deeper feelings to arise; Claire finds herself torn between two men in different times.
Frank searches for his missing wife; a life-changing opportunity arises for Claire as she attempts to come to terms with her marriage to Jamie.
Jamie and the Highlanders rescue Claire from Black Jack Randall; politics threaten the harmony of Clan MacKenzie; Laoghaire tries to win Jamie back.
Jamie hopes the Duke of Sandringham can help remove the price on his head; Claire works to save an abandoned child.
Claire and Geillis stand trial for witchcraft; Claire learns a secret about Geillis' past as Jamie attempts a rescue.
Old wounds are reopened between Jamie and his sister, Jenny, when he returns to his family home with Claire.
Jamie is placed in a tough situation when a redcoat deserter from his past returns; Jenny goes into labor; Jamie and Ian join The Watch.
Claire and Jenny set out to rescue Jamie from his redcoat captors; unorthodox tactics are used to send word to Jamie.
Claire and the Highlanders work on a plan to rescue Jamie; a visit from Black Jack causes Jamie to realize a fate exists that is worse than his death sentence.