Three experts are tasked with finding three compatible couples that will not meet until their wedding; an in-depth exploration of the matchmaking process.
The experts travel back to Chicago to find out the couples' current relationship status; all of the couples gather together to share their experiences and answer questions from viewers.
In Chicago, Pastor Calvin Roberson and his wife, Wendy, celebrate with the participants as they reflect on their journeys; they gather for some goofy games, laughs, highlight reels, and a celebratory look at season five of "Married at First Sight."
The participants are given two weeks to prepare for their weddings including buying rings, dress shopping, getting fitted for tuxedoes and throwing bachelor/bachelorette parties.
Six courageous singles are matched by relationship experts; the participants meet their spouses at their weddings as they vow to legally marry as strangers.
After marrying complete strangers, the newlyweds are alone for the very first time on their wedding night.
Each couple embarks on a honeymoon in hopes of getting to know each other better after marrying as strangers.
Three couples who just married as strangers find themselves testing the marital waters with their new spouse on their honeymoons.
The three couples who married as strangers have known each other for less than a week, but now they must head home and decide where to live.
In just one week, three couples have married as strangers, honeymooned in paradise and moved in together, and now that they're settling in, it's the perfect time for the couples to spend time with their in-laws.
The newlyweds begin living together as married couples; relationship expert Rachel DeAlto pays each couple a visit to help them tackle issues surrounding emotional and physical intimacy.
After marrying as strangers less than four weeks ago, the reality of married life begins to set in; the couples struggle with issues surrounding trust.
Four weeks after the couples got married as strangers, Pastor Calvin Roberson stops by to encourage them to celebrate their first holiday together: Labor Day.
The experts encourage each couple to bring their new spouse to a place from their past that has a special meaning.
The couples reach the halfway point in the experiment; Dr. Pepper Schwartz checks in and reminds the couples that in just one more month they will need to decide if they are going to stay married.
All of the couples struggle in their own ways, so the experts bring them all together to meet each other for the first time in hopes that they can become a support system for one another.
Rachel DeAlto stops by to check in with the three couples to find out how their level of intimacy has been developing.
Before they face the experts one last time, the couples head out of town on a second honeymoon to help gain clarity about their final decisions.