Max works to find a new normal three months after the accident and the birth of his daughter; Kapoor grapples with the stigma of aging; Iggy has a successful day that inspires a life-changing idea; Reynolds deals with an unreliable new intern.
Max invokes a hospital-wide census in an effort to get to know the staff of New Amsterdam on a deeper level; Reynolds takes a leap of faith that lands him in hot water; Dr. Castro extends her treatment plan to more patients in the hospital.
Max takes a chance on a new assistant and goes toe-to-toe with the board on a new plan; Iggy struggles to figure out what is causing a unit-wide illness; Kapoor receives some shocking news.
When Iggy and Kapoor discover a patient might be suffering from lead poisoning, they are forced to take on the city; Max's unsolicited attempts to help a patient backfire.
When Sharpe has a case that hits close to home, she and Max team up to make things right for the patient; Iggy and Bloom are forced to make a tough call on a unique situation.
When women who are on a retreat end up in the ED, Max gets some troubling information that could put a patient in jeopardy; Sharpe and Kapoor work together to mend fences between two feuding sisters.
When Kapoor introduces a patient to Iggy's PTSD group, a creative treatment plan causes turmoil; Sharpe discovers a long-kept secret regarding a patient.
Sharpe lands in hot water when she goes out on a limb for a patient; Max's grief comes to a head; Bloom takes a major step in her recovery.
When an inmate comes in with an entirely preventable illness, Max, Sharpe and Iggy head directly to the source -- Rikers Island; Bloom struggles with her recovery; Reynolds gets news that could change his life.
With the hospital on lockdown after the Rikers patients escape, Sharpe and Max find themselves in a situation that could cost them their lives; Bloom must put aside her pain to help a patient; Iggy is forced to face his marriage's issues.
Max and Luna make friends in an unexpected place as Max struggles with the realities of being a single father; Kapoor takes a big step to help his family.
Sharpe has an important realization that will affect her career; Max and Reynolds take on uncharted waters when a young patient comes to New Amsterdam with symptoms of a heart attack.
The doctors stop at nothing to help their patients after a shocking realization that prompts a change in the hospital; Reynolds must make an important decision in his career.
Max races against the clock to rearrange the budget when faced with employees going unpaid; Kapoor is presented with a device that's the future of medicine; Iggy goes against the norms to prove a diagnosis; Bloom gets an unexpected visitor.
When tasked with turning the opioid epidemic around, Max shuts down the ED and proposes a massive change; Sharpe goes to great lengths to prove a point.
Max, Bloom and Reynolds recount a patient's past encounter that could throw them into a massive lawsuit; Iggy confronts a local middle school about its teaching policies; Kapoor lets his superstitions take over.
Max searches for a solution to crowdfunding after his eye-opening appearance in a viral "Go Fund Me" video; Reynolds takes his last laps at the hospital while Kapoor helps a former pilot deal with his life as a quadriplegic.
When multiple patients begin to show similar alarming symptoms, Sharpe and Bloom scramble to figure out the issue's root; Max works to get a child with a rare muscular disease into the country's only clinical trial that could extend his life.