Dean awakens in a pine box, freed from hell, and has a joyful reunion with Sam and Bobby; Sam, Dean and Bobby wonder what pulled Dean from hell, and what it will want in return.
The spirits of Meg and Agent Henricksen appear and accuse Sam and Dean of failing them; the brothers must save Bobby, who is too crippled with guilt to fight off the ghosts of young children he couldn't save.
Dean is shocked when he is transported back in time to Lawrence, Kan., where he runs into young John Winchester and Mary, who have just fallen in love; Dean enjoys time with his newfound grandfather, who may be hiding a key secret.
Sam and Dean discover a man named Jack who is turning into a Rugaru, a creature that changes from a human into a flesh-eating monster; Sam thinks that Jack can learn to control his urges, but Dean thinks the only honorable thing to do is shoot him.
Dean and Sam investigate when several murders take place at Oktoberfest; Dean thinks a shape-shifter demon is terrorizing the town as iconic monsters from old movies.
Sam and Dean investigate the mystery of several men who apparently died of fright; after Dean becomes infected, Sam and Bobby must find the root of the disease.
Investigating two mysterious deaths in a small town, Sam and Dean discover a witch is sacrificing people to summon a dangerous demon.
Sam and Dean investigate a small town where a working wishing-well brings chaos.
Ruby, Sam and Dean search for Anna, a woman who can hear angel's conversations; Sam tells Dean what happened while he was in hell and how Ruby saved his life.
Anna remembers her past, allowing Sam and Dean to understand why Castiel and Uriel want her dead; Alastair and his demons close in on Anna, Dean and Sam.
Dean and Sam investigate the appearance of a ghost in an abandoned house, but things get more complicated when a family moves in.
A mysterious death brings Dean and Sam to a town full of magicians; Sam and Dean must reverse a spell.
Dean and Sam go under cover to investigate a series of murders at their old high school, and remember their experiences there as students.
Sam and Dean go to a small town in Iowa where three men have beaten their wives to death; a Siren puts Sam and Dean under a spell.
Sam and Dean investigate a town where people are cheating death and discover that the Reapers have gone missing.
Castiel and Uriel ask Dean to use the torturing skills he learned in hell to extract information from Alastair; Dean's world is shattered when Alastair reveals shocking information.
The lives of Sam and Dean if they were not hunters.
Dean and Sam discover a comic book series that accurately details their lives; Chuck reveals that Lilith has a plan for Sam.
A 19-year-old named Adam contacts Dean and Sam, claiming to be John Winchester's son.
Sam and Dean search for Castiel (guest star Misha Collins), but instead find his human vessel, Jimmy.
Bobby and Dean trap Sam in a panic room so he can detox from demon blood; Dean and Sam have a major confrontation.