Sam, Dean and Bobby deal with the aftermath of the devil (Mark Pellegrino) rising from hell; Chuck has stunning news for the brothers.
In hopes of defeating Lucifer, Castiel decides to search for God; Bobby's friend, Rufus, begs for help when demons begin attacking his town.
Sam thinks about giving up hunting; Dean and Castiel team up to search for Raphael.
Sam wants to rejoin Dean in the battle of the apocalypse, but Dean thinks they are better off apart; Dean wakes up five years in the future and is attacked by humans infected with a demonic virus.
Dean and Sam travel to a town when people are being killed by dead icons like Abraham Lincoln; two teenagers claim their friend was kidnapped by Paris Hilton.
Dean and Sam investigate a series of murders that resemble fairy tales and urban legends; the brothers track down an 11-year-old boy that Castiel deems a serious threat.
Dean and Sam learn that a witch is running a poker game where the currency is life years versus money; Dean tries to intervene when Bobby starts losing the game.
Dean and Sam are thrown into an alternate universe by the Trickster where they are characters in different TV series.
A fan tricks Dean and Sam into attending a "Supernatural" fan convention.
Dean, Sam and Castiel try to find Lucifer and send him back to hell.
Dean and Sam check themselves into a mental hospital so they can investigate a monster that is attacking patients.
A teenager creates a body-switching spell and swaps bodies with Sam.
Anna is sent back in time to kill Mary and John Winchester before Sam is conceived.
Castiel helps Dean and Sam find Cupid after people start killing each other for love on Valentine's Day.
Dean and Sam head to Bobby's home town when the dead begin rising from the grave to reunite with their families.
Ambushed by angry hunters, Sam and Dean are shot and killed and sent to heaven; Castiel warns Dean that Zachariah is looking for them in heaven.
Sam and Dean meet a woman in a small town who claims to be a prophet.
The angels come up with a new game plan that horrifies Sam, Dean and Castiel; an old friend returns.
Sam and Dean are kidnapped by a group of gods and held hostage as bargaining chips to stop the apocalypse.
The demon Crowley promises to help Dean and Sam find the remaining Horseman rings so they can trap Lucifer.
Crowley offers to reveal Death's location in exchange for Bobby's soul; Pestilence releases a deadly virus on Sam and Dean.