Callen and Sam work with Navy Capt. Harmon Rabb Jr. to apprehend spies aboard the USS Allegiance; Hetty tries to neutralize a missile attack in the Middle East; Kensi and Deeks are trapped in a mobile CIA unit in Iraq while under attack.
Faced with multiple cases worldwide, the team splits up, with Callen and Sam working in Tel Aviv while Kensi partners with Department of Justice Agent Lance Hamilton in Los Angeles.
Callen and Sam run protection detail for retired Navy Adm. Kilbride in an operation to locate a missing naval intelligence officer.
Callen and Sam are aboard a ship that is placed under quarantine for possible Ebola exposure; Kensi and Deeks investigate the murder of a petty officer who recently departed the ship and is linked to the Ebola exposure.
The team searches for a stolen painting valued at $40 million after online chatter indicates the artwork is being sold on the black market to fund terrorist activity.
The NCIS team reluctantly aligns with two former criminals from England, Ricky Dorsey and Frankie Bolton, after a powerful arms dealer kidnaps Ricky's daughter in an attempt to obtain a dangerous weapons system.
The NCIS team links the theft of an undersea drone prototype to a video game streamer's elaborate party; Callen and Sam cross paths again with insurance broker Katherine Casillas, who insures the gamer's property.
After a Navy lieutenant disappears from the scene of a car accident, the team discovers his laptop is missing along with recently accessed confidential information for retired Navy SEALs.
Callen and Sam travel to San Francisco to search for Beale after he's kidnapped during a clandestine mission for Hetty.
A former Black Ops agent originally recruited and trained by Hetty Lange, returns to seek revenge on Hetty for the life she introduced him to.
The team investigates the theft of a computer virus; Callen and Sam consider their future at the agency; Kensi and Deeks discuss having children; Eric and Nell analyze the impact of Eric's undercover assignment on their relationship.
CIA Officer Veronica Stephens asks the team for help when an agricultural engineer Hetty asked her to bring to the United States disappears.
After a rise in deaths caused by black market opioid use, the NCIS team links the street drug to funding for terrorist activities.
The NCIS team investigates the murder of a Naval warfare engineer at a spoken poetry event; Callen asks Nell to assist him in a worldwide search for Anna's whereabouts.
Anna Kolcheck returns to warn Callen that he is in danger and he must now work with an archenemy to stop an underground trafficking ring.
When Fatima is captured while on a mission and held for ransom, Callen and Sam enlist an undercover CIA agent to help get her back.
When an FBI agent is killed while trying to track the location of an undercover agent, NCIS must find the missing agent before the criminals find him.
The team investigates the disappearance of a department of defense officer who was looking into a recent UFO sighting; Anna makes a bold decision about her future.
While Sam investigates the murder of an Iranian, he must also try to save a new agent who accidentally triggers a bomb; Nell makes a decision about her future.
The team assists the DOJ in the investigation of an arsonist who targets an FBI safe house that's protecting a political activist seeking asylum; Eric deals with the aftermath of Nell leaving the team.
The team helps a former NCIS tech operator search for her missing ex-partner, whom they fear might be working with the gun runners they failed to take down years ago; Deeks reels when his bar gets a negative review.
Sam, Callen and Rountree travel to Afghanistan to help with a sensitive case after two SEALs claim their chief murdered an unarmed prisoner.